{"id":2981,"date":"2020-07-23T20:17:44","date_gmt":"2020-07-23T20:17:44","guid":{"rendered":"https:\/\/www.priorclave.com\/en-us\/?p=2981"},"modified":"2020-06-30T20:30:15","modified_gmt":"2020-06-30T20:30:15","slug":"minding-the-details-in-bsl-3-and-other-medical-research-labs","status":"publish","type":"post","link":"https:\/\/www.priorclave.com\/en-us\/2020\/07\/23\/minding-the-details-in-bsl-3-and-other-medical-research-labs\/","title":{"rendered":"Minding the Details in BSL-3 and Other Medical Research Labs"},"content":{"rendered":"<p class=\"p5\"><span class=\"s2\"> Coronavirus has disrupted and altered our public life quickly and, perhaps, irrevocably. Scientists have studied the coronavirus safely for years in BSL-3 (&#8220;<a href=\"http:\/\/en.wikipedia.org\/wiki\/Biosafety_level%23Biosafety_level_3\"><span class=\"s3\">biosafety level 3<\/span><\/a>&#8220;) labs at undisclosed locations around the world. And while our interest in the progress of their work may be at its apex, the scientists doing the work are carrying on using the same methodical rigor that have long been the hallmark of the BSL-3 designation.<\/span><\/p>\n<p class=\"p5\"><span class=\"s2\"> In the U.S., the CDC designates four levels of labs. BSL-3 labs specialize in microbes that can become aerosolized and cause major illness, injury, or death. This includes coronavirus.<img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-2924 size-medium\" src=\"https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-300x169.jpg\" alt=\"novel coronavirus\/COVID-19\" width=\"300\" height=\"169\" srcset=\"https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-300x169.jpg 300w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-1024x576.jpg 1024w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-768x432.jpg 768w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-64x36.jpg 64w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-128x72.jpg 128w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-240x135.jpg 240w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-320x180.jpg 320w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-360x203.jpg 360w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-375x211.jpg 375w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-480x270.jpg 480w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-540x304.jpg 540w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-640x360.jpg 640w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-720x405.jpg 720w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-800x450.jpg 800w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2-960x540.jpg 960w, https:\/\/www.priorclave.com\/en-us\/wp-content\/uploads\/sites\/3\/2020\/04\/Coronavirus_SARS-CoV-2.jpg 1280w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/span><\/p>\n<p class=\"p5\"><span class=\"s2\"> Because of the seriousness of their handled materials, BSL-3 labs are &#8220;<a href=\"https:\/\/pca.st\/episode\/665602b5-cc13-4e87-960d-9f3717f2cff2\"><span class=\"s4\">slow labs<\/span><\/a>&#8220;\u2014places where workers plan their workflows carefully in advance. They work methodically, from checklists, one step at a time. Essential PPE and biological safety cabinets enclose and contain contaminated surfaces of all kinds within the lab. Staff are medically monitored. Safety processes carefully defined.<\/span><\/p>\n<h2 class=\"p7\"><span class=\"s2\">Slow and Easy Wins the Race in BSL-3 Labs\u00a0<\/span><\/h2>\n<p class=\"p5\"><span class=\"s2\">Researchers build slowness into the BSL-3 workflow. As Vanderbilt\u2019s <a href=\"http:\/\/pca.st\/5t7lf3ni\"><span class=\"s3\">Dr. Mark Denison explained in a recent episode of <i>Radio Lab<\/i><\/span><\/a><i>, &#8220;<\/i>No one can tell you to speed up when you\u2019re in the BSL-3.\u201d<\/span><\/p>\n<p class=\"p5\"><span class=\"s2\"> The BSL-3 lab at Vanderbilt University Medical Center took more than two years to design and build to safety specifications. As Dr. Denison sees it:<\/span><\/p>\n<blockquote>\n<p class=\"p5\"><span class=\"s2\"> \u201cThis [work on the novel coronavirus] is too urgent to go fast. \u2026 Work in BSL-3 is hyper methodical. You do one thing at a time. \u2026 You do everything with an intentionality that is sort of &#8216;anti&#8217; how we&#8217;re trained to move forward fast and do lots of things in a day.\u2026 <\/span><span class=\"s2\">Everything is written down, you follow the guidelines, you follow them one step at a time.\u2026 You can\u2019t answer a phone, you can\u2019t respond to an email. The world sort of comes to a stop while you\u2019re working in there.&#8221;<\/span><\/p>\n<\/blockquote>\n<p class=\"p5\"><span class=\"s2\"> Researchers hope to bring intentionality and mindfulness to any scientific inquiry. But it is even more important when they&#8217;re working with substances that could cause significant injury, illness, or even death when not safely handled. <\/span><\/p>\n<p class=\"p5\"><span class=\"s2\">These &#8220;clean-room&#8221; setups are <a href=\"https:\/\/www.priorclave.com\/en-us\/2020\/06\/18\/cannabis-testing-equipment-consumer-protection\/\"><span class=\"s4\">increasingly common<\/span><\/a> beyond pathogen containment. We\u2019ve worked with several organizations on clean room and BSL projects. We appreciate their methodical approach to work\u2014and match it with a methodical approach to ours. Our custom <a href=\"https:\/\/www.priorclave.com\/en-us\/autoclaves\/pass-through-autoclaves\/\"><span class=\"s4\">pass-through autoclaves<\/span><\/a> provide sterile routes into and out of these sealed laboratory environments, reducing the risk of compromised laboratory standards, contamination, or infection\u2014in BSL-3 labs and beyond.\u00a0<\/span><\/p>\n<h2 class=\"p7\"><span class=\"s2\">BioMaster for Safer Surfaces<\/span><\/h2>\n<p class=\"p5\"><span class=\"s2\">High-stakes situations aren&#8217;t the only time we&#8217;re interested in preventing <\/span><span class=\"s2\">cross-contamination<\/span><span class=\"s2\">.\u00a0 Every Priorclave autoclave\u2014not just those destined for sensitive BSL-3 environments\u2014come with <a href=\"https:\/\/www.priorclave.com\/en-us\/why-priorclave\/autoclave-features\/\"><span class=\"s4\">Biomaster Protected\u00ae Antimicrobial coating as standard<\/span><\/a>. This <a href=\"https:\/\/www.priorclave.com\/en-gb\/wp-content\/uploads\/sites\/2\/2019\/07\/Biomaster-Datasheet.pdf\"><span class=\"s4\">anti-bacterial and anti-fungal coating<\/span><\/a> also has <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3199605\/\"><span class=\"s4\">virucidal qualities<\/span><\/a>, and is incorporated into the body of our machines to stay with them for the life of the product, offering passive protection from cross contamination over the long haul.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Coronavirus has disrupted and altered our public life quickly and, perhaps, irrevocably. Scientists have studied the coronavirus safely for years in BSL-3 (&#8220;biosafety level 3&#8220;) labs at undisclosed locations around [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":2561,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[320],"tags":[439,438,437,430,440,431],"class_list":["post-2981","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lab-design","tag-biosafety-level-three","tag-bsl","tag-bsl-3","tag-coronavirus","tag-covid","tag-covid-19"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Minding the Details in BSL-3 and Other Medical Research Labs<\/title>\n<meta name=\"description\" content=\"Scientists safely study diseases like coronavirus\u2014ones that can become aerosolized and cause major illness, 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